A new study led by Margaret Honein at the U.S. Centers for Disease Control and Prevention’s National Center on Birth Defects and Developmental Disabilities, indicate that premature babies born in the United States are more than twice as likely to have a major birth defect than full-term infants.

According to the study, babies born between 24 and 31 weeks gestation were at the highest risk for birth defects. Margaret Honein, said: “Pre-term birth affects about 12 percent of infants born in the United States. And birth defects affect about 3 percent of births in the U.S. And we think it’s important to recognize the pretty strong association between these two serious outcomes.”

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